Diaz-Griffero Lab
Publications
92. Manganaro L, Hong P, Hernandez MM, Argyle D, Mulder LCF, Potla U, Diaz-Griffero F, Lee B, Fernandez-Sesma A, Simon V. IL-15 regulates susceptibility of CD4+ T cells to HIV infection. Proc Natl Acad Sci U S A. 2018, Oct; DOI: 10.1073/pnas.1806695115
91. Martinez-Lopez A, Martin-Fernandez M, Buta S, Kim B, Bogunovic D, Diaz-Griffero F. SAMHD1 deficient human monocytes autonomously trigger type 1 interferon. Mol Immunol. 2018 Sep; DOI: 10.1016/j.molimm.2018.08.005
90. Selyutina A, Bulnes-Ramos A, Diaz-Griffero F. Binding of host factors to stabilized HIV-1 capsid tubes. Binding of host factors to stabilized HIV-1 capsid tubes. Virology. 2018 Oct; DOI: 10.1016/j.virol.2018.07.019
89. Wang Z, Bhattacharya A, White T, Buffone C, McCabe A, Nguyen LA, Shepard CN, Pardo S, Kim B, Weintraub ST, Demeler B, Diaz-Griffero F, Ivanov DN. Functionality of redox-active cysteines is required for restriction of retroviral replication by SAMHD1. Cell Rep. 2018 Jul; DOI: 10.1016/j-celrep.2018.06.090
88. Said EA, Diaz-Griffero F, Bonte D, Lamarre D, Al-Jabri AA. Immune response to RNA viruses. J Immunol Res. 2018 Jun; DOI: 10.1155/2018/5473678
87. Buffone C, Martinez-Lopez A, Fricke T, Opp S, Severgnini M, Cifola I, Petiti L, Frabetti S, Skorupka K, Zadrozny KK, Ganser-Pornillos BK, Pornillos O, Di Nunzio F, Diaz-Griffero F. Nup153 unlocks the nuclear pore complex for HIV-1 nuclear translocation in nondividing cells. J Virol. 2018 Sep; DOI: 10.1128/JVI.00648-18
86. Schott K, Fuchs NV, Derua R, Mahboubi B, Schnellbächer E, Seifried J, Tondera C, Schmitz H, Shepard C, Brandariz-Nuñez A, Diaz-Griffero F, Reuter A, Kim B, Janssens V, König R. Dephosphorylation of the HIV-1 restriciton factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit. Nat Commun. 2018 Jun; DOI: 10.1038/s41467-018-04671-1
85. Persaud M, Martinez-Lopez A, Buffone C, Porcelli SA, Diaz-Griffero F. Infection by Zika viruses requires the transmembrane protein AXL, endocytosis and low pH. Virology. 2018 Mar; DOI: 10.1016/j.virol.2018.03.009
84. Meyerson NR, Warren CJ, Vieira DASA, Diaz-Griffero F, Sawyer SL. Species-specific vulnerability of RanBP2 shaped the evolution of SIV as it transmitted in African apes. PloS Pathog. 2018 Apr; DOI: 10.1371/journal.ppat.1006983
83. Schulte B, Selyutina A, Opp S, Herschhorn A, Sodroski JG, Diaz-Griffero F. Localization to detergen-resistant membranes and HIV-1 core entry inhibition correlate with HIV-1 restriction by SERINC5. Virology. 2018 Feb; DOI: 10.1016/j.virol.2017.12.005
82. Dharan A, Opp S, Abdel-Rahim O, Keceli SK, Imam S, Diaz-Griffero F, Campbell EM. Bicaudal D2 facilitates the cytoplasmic trafficking and nuclear import of HIV-1 genomes during infection. Proc Natl Acad Sci U S A. 2017 Nov; DOI: 10/1073/pnas.1712033114
81. White TE, Brandariz-Nuñez A, Martinez-Lopez A, Knowlton C, Lenzi G, Kim B, Ivanov D, Diaz-Griffero F. A SAMHD1 mutation associated with Aicardi-Goutières syndrome uncouples the ability of SAMHD1 to restrict HIV-1 from its ability to downmodulate type I interferon in humans. Hum Mutat. 2017 Jun; DOI: 10.1002/humu.23201
80. Opp S, Fricke T, Shepard C, Kovalskyy D, Bhattacharya A, Herkules F, Ivanov DN, Kim B, Valle-Casuso J, Diaz-Griffero F. The small-molecule 3G11 inhibits HIV-1 reverse transcription. Chem Biol Drug Des. 2016 Oct; DOI:10.1111/cbdd.12886
79. Wang Z, Bhattacharya A, Villacorta J, Diaz-Griffero F, Ivanon DN. Allosteric activation of SAMHD1 protein by deoxynucleotide triphosphate (dNTP)-dependent tetramerization requires dNTP concentration that are similar to dNTP concentrations observed in cycling T cells. J. Biol. Chem. 2016 Oct; 291(41): 21407-21413. DOI:10.1074/jbc.C116.751446
78. Bhattacharya A, Wang Z, White T, Buffone C, Nguyen LA, Shepard CN, Kim B, Demeler B, Diaz-Griffero F, Ivanov DN. Effects of T592 phosphomimetic mutations on tetramer stability and dNTPase activity of SAMHD1 can not explain the retroviral restriction defect. Sci Rep. 2016 Aug; 6: 31353. DOI:10.1038/srep31353
77. White TE, Brandariz-Nuñez A, Han K, Sawyer SL, Kim B, Diaz-Griffero F. Modulation of LINE-1 retrotransposition by a human SAMHD1 polymorphism. Virology Reports. 2016 Dec; 6: 53-60. DOI:
76. Nepveu-Traversy MÉ, Demogines A, Fricke T, Plourde MB, Riopel K, Veillette M, Diaz-Griffero F, Sawyer SL, Berthoux L. A putative SUMO interacting motif in the B30.2/SPRY domain of rhesus macaque TRIM5α important for NF-κB/AP-1 signaling and HIV-1 restriction. Heliyon. 2016 Jan 1;2(1). DOI: 10.1016/j.heliyon.2015.e00056
75. Chen NY, Zhou L, Gane PJ, Opp S, Ball NJ, Nicastro G, Zufferey M, Buffone C, Luban J, Selwood D, Diaz-Griffero F, Taylor I, Fassati A. HIV-1 capsid is involved in post-nucelar entry steps. Retrovirology. 2016 Apr; 13:28. DOI: 10.1186/s12977-016-0262-0
74. Thenin-Houssier S, De Vera IMS, Pedro-Rosa L, Brady A, Richard A, Konnick B, Opp S, Buffone C, Fuhrmann J, Kota S, Billack B, Pietka-Ottlik M, Tellinghuisen T, Choe H, Spicer T, Scampavia L, Diaz-Griffero F, Kojetin DJ, Valentea ST. Ebselen, a small-molecule capsid inhibitor of HIV-1 replication. Antimicrobial Agents and Chemotherapy. 2016 Apr 1;60(4):2195-2208. DOI: 10.1128/AAC.02574-15
73. Fricke T, Diaz-Griffero F. HIV-1 capsid stabilization assay. In Methods in Molecular Biology. Vol. 1354. Humana Press Inc.2016. p. 39-47. (Methods in Molecular Biology). DOI: 10.1007/978-1-4939-3046-3_3
72. White TE, Brandariz-Nuñez A, Han K, Sawyer SL, Kim B, Diaz-Griffero F. Modulation of LINE-1 retrotransposition by a human SAMHD1 polymorphism. Virology Reports. 2016 Dec 1;6:53-60. DOI: 10.1016/j.virep.2016.06.001
71. Opp S, Vieira DASA, Schulte B, Chanda SK, Diaz-Griffero F. MxB is not responsible for the blocking of HIV-1 infection observed in alpha interferontreated cells. Journal of Virology. 2016;90(6):3056-3064. DOI: 10.1128/JVI.03146-15
70. Donahue DA, Amraoui S, di Nunzio F, Kieffer C, Porrot F, Opp S, Diaz-Griffero F, Casartelli N, Schwartz O. SUN2 overexpression deforms nuclear shape and inhibits HIV. Journal of Virology. 2016 Apr 1;90(8):4199-4214. DOI: 10.1128/JVI.03202-15
69. Campbell EM, Weingart J, Sette P, Opp S, Sastri J, O'Connor SK, Talley S, Diaz-Griffero F, Hirsch V, Bouamrb F. TRIM5α-mediated ubiquitin chain conjugation is required for inhibition of HIV-1 reverse transcription and capsid destabilization. Journal of Virology. 2016;90(4):1849-1857. DOI: 10.1128/JVI.01948-15
68. Lelek M, Casartelli N, Pellin D, Rizzi E, Souque P, Severgnini M, Di Serio C, Fricke T, Diaz-Griffero F, Zimmer C, Charneau P, Di Nunzio F. Chromatin organization at the nuclear pore favours HIV replication. Nature Communications. 2015;6. 7483. DOI: 10.1038/ncomms7483
67. Posch W, Steger M, Knackmuss U, Blatzer M, Baldauf HM, Doppler W, White TE, Hörtnagl P, Diaz-Griffero F, Lass-Flörl C, Hackl H, Moris A, Keppler OT, Wilflingsederet D. Complement-Opsonized HIV-1 Overcomes Restriction in Dendritic Cells. PLoS Pathogens. 2015 Jun 1;11(6). e1005005. DOI: 10.1371/journal.ppat.1005005
66. Schulte B, Buffone C, Opp S, Di Nunzio F, Augusto De Souza Aranha Vieira D, Brandariz-Nuñez A, Diaz-Griffero F. Restriction of HIV-1 Requires the N-terminal Region of MxB/Mx2 as a Capsid-Binding Motif but not as a Nuclear Localization Signal. J Virol. 2015 Jun 10. pii: JVI.00753-15. [Epub ahead of print] PubMed PMID: 26063425.
65. Malikov V, da Silva ES, Jovasevic V, Bennett G, de Souza Aranha Vieira DA, Schulte B, Diaz-Griffero F, Walsh D, Naghavi MH. HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus. Nat Commun. 2015 Mar 30;6:6660. doi: 10.1038/ncomms7660. PubMed PMID: 25818806; PubMed Central PMCID: PMC4380233.
64. Lelek M, Casartelli N, Pellin D, Rizzi E, Souque P, Severgnini M, Di Serio C, Fricke T, Diaz-Griffero F, Zimmer C, Charneau P, Di Nunzio F. Chromatin organization at the nuclear pore favours HIV replication. Nat Commun. 2015 Mar 6; 6: 6483. doi: 10.1038/ncomms7483. PubMed PMID: 25744187; PubMed Central PMCID: PMC4366494.
63. Buffone C, Schulte B, Opp S, Diaz-Griffero F. Contribution of MxB oligomerization to HIV-1 capsid binding and restriction. J Virol. 2015 Mar;89(6):3285-94. doi: 10.1128/JVI.03730-14. Epub 2015 Jan 7. PubMed PMID: 25568212; PubMed Central PMCID: PMC4337540.
62. Bhattacharya A, Alam SL, Fricke T, Zadrozny K, Sedzicki J, Taylor AB, Demeler B, Pornillos O, Ganser-Pornillos BK, Diaz-Griffero F, Ivanov DN, Yeager M. Structural basis of HIV-1 capsid recognition by PF74 and CPSF6. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18625-30. doi: 10.1073/pnas.1419945112. Epub 2014 Dec 17. PubMed PMID: 25518861; PubMed Central PMCID: PMC4284599.
61. Fricke T, Buffone C, Opp S, Valle-Casuso J, Diaz-Griffero F. BI-2 destabilizes HIV-1 cores during infection and Prevents Binding of CPSF6 to the HIV-1 Capsid. Retrovirology. 2014 Dec 11;11:120. doi: 10.1186/s12977-014-0120-x. PubMed PMID: 25496772; PubMed Central PMCID: PMC4271331.
60. Lukic Z, Dharan A, Fricke T, Diaz-Griffero F, Campbell EM. HIV-1 uncoating is facilitated by dynein and kinesin 1. J Virol. 2014 Dec;88(23):13613-25. doi: 10.1128/JVI.02219-14. Epub 2014 Sep 17. PubMed PMID: 25231297; PubMed Central PMCID: PMC4248982.
59. Hollenbaugh JA, Tao S, Lenzi GM, Ryu S, Kim DH, Diaz-Griffero F, Schinazi RF, Kim B. dNTP pool modulation dynamics by SAMHD1 protein in monocyte-derived macrophages. Retrovirology. 2014 Aug 27;11:63. doi: 10.1186/s12977-014-0063-2. PubMed PMID: 25158827; PubMed Central PMCID: PMC4161909.
58. Fricke T, White TE, Schulte B, de Souza Aranha Vieira DA, Dharan A, Campbell EM, Brandariz-Nuñez A, Diaz-Griffero F. MxB binds to the HIV-1 core and prevents the uncoating process of HIV-1. Retrovirology. 2014 Aug 14;11:68. doi: 10.1186/PREACCEPT-6453674081373986. PubMed PMID: 25123063; PubMed Central PMCID: PMC4145229.
57. Sastri J, Johnsen L, Smolin N, Imam S, Mukherjee S, Lukic Z, Brandariz-Nuñez A, Robia SL, Diaz-Griffero F, Wiethoff C, Campbell EM. Restriction of HIV-1 by rhesus TRIM5α is governed by alpha helices in the Linker2 region. J Virol. 2014 Aug;88(16):8911-23. doi: 10.1128/JVI.01134-14. Epub 2014 May 28. PubMed PMID: 24872590; PubMed Central PMCID: PMC4136267.
56. Ryoo J, Choi J, Oh C, Kim S, Seo M, Kim SY, Seo D, Kim J, White TE, Brandariz-Nuñez A, Diaz-Griffero F, Yun CH, Hollenbaugh JA, Kim B, Baek D, Ahn K. The ribonuclease activity of SAMHD1 is required for HIV-1 restriction. Nat Med. 2014 Aug;20(8):936-41. doi: 10.1038/nm.3626. Epub 2014 Jul 20. PubMed PMID: 25038827; PubMed Central PMCID: PMC4318684.
55. White TE, Brandariz-Nuñez A, Valle-Casuso JC, Knowlton C, Kim B, Sawyer SL, Diaz-Griffero F. Effects of human SAMHD1 polymorphisms on HIV-1 susceptibility. Virology. 2014 Jul;460-461:34-44. doi: 10.1016/j.virol.2014.04.023. Epub 2014 May 29. PubMed PMID: 25010268; PubMed Central PMCID: PMC4101048.
54. St Gelais C, de Silva S, Hach JC, White TE, Diaz-Griffero F, Yount JS, Wu L. Identification of cellular proteins interacting with the retroviral restriction factor SAMHD1. J Virol. 2014 May;88(10):5834-44. doi: 10.1128/JVI.00155-14. Epub 2014 Mar 12. Erratum in: J Virol. 2014 Jul;88(13):7689. PubMed PMID: 24623419; PubMed Central PMCID: PMC4019113.
53. Yang Y, Brandariz-Nuñez A, Fricke T, Ivanov DN, Sarnak Z, Diaz-Griffero F. Binding of the rhesus TRIM5α PRYSPRY domain to capsid is necessary but not sufficient for HIV-1 restriction. Virology. 2014 Jan 5;448:217-28. doi: 10.1016/j.virol.2013.10.012. Epub 2013 Oct 31. PubMed PMID: 24314652; PubMed Central PMCID: PMC3900861.
52. Yang Y, Luban J, Diaz-Griffero F. The fate of HIV-1 capsid: a biochemical assay for HIV-1 uncoating. Methods Mol Biol. 2014;1087:29-36. doi: 10.1007/978-1-62703-670-2_3. PubMed PMID: 24158811; PubMed Central PMCID: PMC4317566.
51. Brojatsch J, Lima H, Kar AK, Jacobson LS, Muehlbauer SM, Chandran K, Diaz-Griffero F. A proteolytic cascade controls lysosome rupture and necrotic cell death mediated by lysosome-destabilizing adjuvants. PLoS One. 2014 Jun 3;9(6):e95032. doi: 10.1371/journal.pone.0095032. eCollection 2014. PubMed PMID: 24893007; PubMed Central PMCID: PMC4043491.
50. Biris N, Tomashevski A, Bhattacharya A, Diaz-Griffero F, Ivanov DN. Rhesus monkey TRIM5α SPRY domain recognizes multiple epitopes that span several capsid monomers on the surface of the HIV-1 mature viral core. J Mol Biol. 2013 Dec 13;425(24):5032-44. doi: 10.1016/j.jmb.2013.07.025. Epub 2013 Jul 23. PubMed PMID: 23886867; PubMed Central PMCID: PMC4116666.
49. Kim ET, White TE, Brandariz-Núñez A, Diaz-Griffero F, Weitzman MD. SAMHD1 restricts herpes simplex virus 1 in macrophages by limiting DNA replication. J Virol. 2013 Dec;87(23):12949-56. doi: 10.1128/JVI.02291-13. Epub 2013 Sep 25. PubMed PMID: 24067963; PubMed Central PMCID: PMC3838123.
48. Brandariz-Nuñez A, Valle-Casuso JC, White TE, Nguyen L, Bhattacharya A, Wang Z, Demeler B, Amie S, Knowlton C, Kim B, Ivanov DN, Diaz-Griffero F. Contribution of oligomerization to the anti-HIV-1 properties of SAMHD1. Retrovirology. 2013 Nov 12;10:131. doi: 10.1186/1742-4690-10-131. PubMed PMID: 24219908; PubMed Central PMCID: PMC3882887.
47. Fricke T, Brandariz-Nuñez A, Wang X, Smith AB 3rd, Diaz-Griffero F. Human cytosolic extracts stabilize the HIV-1 core. J Virol. 2013 Oct;87(19):10587-97. doi: 10.1128/JVI.01705-13. Epub 2013 Jul 24. PubMed PMID: 23885082; PubMed Central PMCID: PMC3807412.
46. Lima H Jr, Jacobson LS, Goldberg MF, Chandran K, Diaz-Griffero F, Lisanti MP, Brojatsch J. Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death. Cell Cycle. 2013 Jun 15;12(12):1868-78. doi: 10.4161/cc.24903. Epub 2013 May 20. PubMed PMID: 23708522; PubMed Central PMCID: PMC3735701.
45. Di Nunzio F, Fricke T, Miccio A, Valle-Casuso JC, Perez P, Souque P, Rizzi E, Severgnini M, Mavilio F, Charneau P, Diaz-Griffero F. Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication. Virology. 2013 May 25;440(1):8-18. doi: 10.1016/j.virol.2013.02.008. Epub 2013 Mar 21. PubMed PMID: 23523133; PubMed Central PMCID: PMC3860269.
44. Pham QT, Veillette M, Brandariz-Nuñez A, Pawlica P, Thibert-Lefebvre C, Chandonnet N, Diaz-Griffero F, Berthoux L. A novel aminoacid determinant of HIV-1 restriction in the TRIM5α variable 1 region isolated in a random mutagenic screen. Virus Res. 2013 May;173(2):306-14. doi: 10.1016/j.virusres.2013.01.013. Epub 2013 Jan 25. PubMed PMID: 23357295; PubMed Central PMCID: PMC4317569.
43. Fricke T, Valle-Casuso JC, White TE, Brandariz-Nuñez A, Bosche WJ, Reszka N, Gorelick R, Diaz-Griffero F. The ability of TNPO3-depleted cells to inhibit HIV-1 infection requires CPSF6. Retrovirology. 2013 Apr 26;10:46. doi: 10.1186/1742-4690-10-46. PubMed PMID: 23622145; PubMed Central PMCID: PMC3695788.
42. White TE, Brandariz-Nuñez A, Valle-Casuso JC, Amie S, Nguyen LA, Kim B, Tuzova M, Diaz-Griffero F. The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation. Cell Host Microbe. 2013 Apr 17;13(4):441-51. doi: 10.1016/j.chom.2013.03.005. PubMed PMID: 23601106; PubMed Central PMCID: PMC3864637.
41. Jacobson LS, Lima H Jr, Goldberg MF, Gocheva V, Tsiperson V, Sutterwala FS, Joyce JA, Gapp BV, Blomen VA, Chandran K, Brummelkamp TR, Diaz-Griffero F, Brojatsch J. Cathepsin-mediated necrosis controls the adaptive immune response by Th2 (T helper type 2)-associated adjuvants. J Biol Chem. 2013 Mar 15;288(11):7481-91. doi: 10.1074/jbc.M112.400655. Epub 2013 Jan 7. PubMed PMID: 23297415; PubMed Central PMCID: PMC3597789.
40. White TE, Brandariz-Nuñez A, Valle-Casuso JC, Amie S, Nguyen L, Kim B, Brojatsch J, Diaz-Griffero F. Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1. Virology. 2013 Feb 5;436(1):81-90. doi: 10.1016/j.virol.2012.10.029. Epub 2012 Nov 13. PubMed PMID: 23158101; PubMed Central PMCID: PMC3767443.
39. Brandariz-Nuñez A, Roa A, Valle-Casuso JC, Biris N, Ivanov D, Diaz-Griffero F. Contribution of SUMO-interacting motifs and SUMOylation to the antiretroviral properties of TRIM5α. Virology. 2013 Jan 20;435(2):463-71. doi: 10.1016/j.virol.2012.09.042. Epub 2012 Oct 16. PubMed PMID: 23084420; PubMed Central PMCID: PMC3534947.
38. Yang Y, Fricke T, Diaz-Griffero F. Inhibition of reverse transcriptase activity increases stability of the HIV-1 core. J Virol. 2013 Jan;87(1):683-7. doi: 10.1128/JVI.01228-12. Epub 2012 Oct 17. PubMed PMID: 23077298; PubMed Central PMCID: PMC3536417.
37. Fassler M, Weissberg I, Levy N, Diaz-Griffero F, Monsonego A, Friedman A, Taube R. Preferential lentiviral targeting of astrocytes in the central nervous system. PLoS One. 2013 Oct 2;8(10):e76092. doi: 10.1371/journal.pone.0076092. eCollection 2013. PubMed PMID: 24098426; PubMed Central PMCID: PMC3788778.
36. Welbourn S, Miyagi E, White TE, Diaz-Griffero F, Strebel K. Identification and characterization of naturally occurring splice variants of SAMHD1. Retrovirology. 2012 Oct 23;9:86. doi: 10.1186/1742-4690-9-86. PubMed PMID: 23092512; PubMed Central PMCID: PMC3503569.
35. Biris N, Yang Y, Taylor AB, Tomashevski A, Guo M, Hart PJ, Diaz-Griffero F, Ivanov DN. Structure of the rhesus monkey TRIM5α PRYSPRY domain, the HIV capsid recognition module. Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13278-83. doi: 10.1073/pnas.1203536109. Epub 2012 Jul 30. PubMed PMID: 22847415; PubMed Central PMCID: PMC3421187.
34. Brandariz-Nuñez A, Valle-Casuso JC, White TE, Laguette N, Benkirane M, Brojatsch J, Diaz-Griffero F. Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac. Retrovirology. 2012 Jun 12;9:49. doi: 10.1186/1742-4690-9-49. PubMed PMID: 22691373; PubMed Central PMCID: PMC3410799.
33. Valle-Casuso JC, Di Nunzio F, Yang Y, Reszka N, Lienlaf M, Arhel N, Perez P, Brass AL, Diaz-Griffero F. TNPO3 is required for HIV-1 replication after nuclear import but prior to integration and binds the HIV-1 core. J Virol. 2012 May;86(10):5931-6. doi: 10.1128/JVI.00451-12. Epub 2012 Mar 7. PubMed PMID: 22398280; PubMed Central PMCID: PMC3347269.
32. Roa A, Hayashi F, Yang Y, Lienlaf M, Zhou J, Shi J, Watanabe S, Kigawa T, Yokoyama S, Aiken C, Diaz-Griffero F. RING domain mutations uncouple TRIM5α restriction of HIV-1 from inhibition of reverse transcription and acceleration of uncoating. J Virol. 2012 Feb;86(3):1717-27. doi: 10.1128/JVI.05811-11. Epub 2011 Nov 23. PubMed PMID: 22114335; PubMed Central PMCID: PMC3264337.
31. Diaz-Griffero F. The Role of TNPO3 in HIV-1 Replication. Mol Biol Int. 2012;2012:868597. doi: 10.1155/2012/868597. Epub 2012 Jul 19. PubMed PMID: 22888429; PubMed Central PMCID: PMC3409535.
30. Di Nunzio F, Danckaert A, Fricke T, Perez P, Fernandez J, Perret E, Roux P, Shorte S, Charneau P, Diaz-Griffero F, Arhel NJ. Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration. PLoS One. 2012;7(9):e46037. doi: 10.1371/journal.pone.0046037. Epub 2012 Sep 25. Erratum in: PLoS One. 2013;8(12).doi:10.1371/annotation/34f46796-5d53-4a23-b3df-b599b0369eb9. PubMed PMID: 23049930; PubMed Central PMCID: PMC3457934.
29. Lienlaf M, Hayashi F, Di Nunzio F, Tochio N, Kigawa T, Yokoyama S, Diaz-Griffero F. Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha. J Virol. 2011 Sep;85(17):8725-37. doi: 10.1128/JVI.00497-11. Epub 2011 Jul 6. PubMed PMID: 21734049; PubMed Central PMCID: PMC3165826.
28. Diaz-Griffero F, Gallo DE, Hope TJ, Sodroski J. Trafficking of some old world primate TRIM5α proteins through the nucleus. Retrovirology. 2011 May 15;8:38. doi: 10.1186/1742-4690-8-38. PubMed PMID: 21575157; PubMed Central PMCID: PMC3120760.
27. Diaz-Griffero F. Caging the beast: TRIM5α binding to the HIV-1 core. Viruses. 2011 May;3(5):423-8. doi: 10.3390/v3050423. Epub 2011 Apr 27. PubMed PMID: 21994740; PubMed Central PMCID: PMC3186010.
26. Sastri J, O'Connor C, Danielson CM, McRaven M, Perez P, Diaz-Griffero F, Campbell EM. Identification of residues within the L2 region of rhesus TRIM5alpha that are required for retroviral restriction and cytoplasmic body localization. Virology. 2010 Sep 15;405(1):259-66. doi: 10.1016/j.virol.2010.06.015. Epub 2010 Jul 14. PubMed PMID: 20633914; PubMed Central PMCID: PMC2914212.
25. Peña-Cruz V, McDonough SM, Diaz-Griffero F, Crum CP, Carrasco RD, Freeman GJ.PD-1 on immature and PD-1 ligands on migratory human Langerhans cells regulate antigen-presenting cell activity. J Invest Dermatol. 2010 Sep;130(9):2222-30. doi: 10.1038/jid.2010.127. Epub 2010 May 6. PubMed PMID: 20445553; PubMed Central PMCID: PMC2927196.
24. Gosselin A, Monteiro P, Chomont N, Diaz-Griffero F, Said EA, Fonseca S, Wacleche V, El-Far M, Boulassel MR, Routy JP, Sekaly RP, Ancuta P. Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cells are highly permissive to HIV-1 infection. J Immunol. 2010 Feb 1;184(3):1604-16. doi: 10.4049/jimmunol.0903058. Epub 2009 Dec 30. PubMed PMID: 20042588; PubMed Central PMCID: PMC4321756.
23. Mani M, Carrasco DE, Zhang Y, Takada K, Gatt ME, Dutta-Simmons J, Ikeda H, Diaz-Griffero F, Pena-Cruz V, Bertagnolli M, Myeroff LL, Markowitz SD, Anderson KC, Carrasco DR. BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells. Cancer Res. 2009 Oct 1;69(19):7577-86. doi: 10.1158/0008-5472.CAN-09-0773. Epub 2009 Sep 8. PubMed PMID: 19738061; PubMed Central PMCID: PMC4321734.
22. Diaz-Griffero F, Qin XR, Hayashi F, Kigawa T, Finzi A, Sarnak Z, Lienlaf M, Yokoyama S, Sodroski J. A B-box 2 surface patch important for TRIM5alpha self-association, capsid binding avidity, and retrovirus restriction. J Virol. 2009 Oct;83(20):10737-51. doi: 10.1128/JVI.01307-09. Epub 2009 Aug 5. PubMed PMID: 19656869; PubMed Central PMCID: PMC2753111.
21. Torimiro JN, Javanbakht H, Diaz-Griffero F, Kim J, Carr JK, Carrington M, Sawitzke J, Burke DS, Wolfe ND, Dean M, Sodroski J. A rare null allele potentially encoding a dominant-negative TRIM5alpha protein in Baka pygmies. Virology. 2009 Aug 15;391(1):140-7. doi: 10.1016/j.virol.2009.05.038. Epub 2009 Jul 3. PubMed PMID: 19577266; PubMed Central PMCID: PMC2760473.
20. Kar AK, Diaz-Griffero F, Li Y, Li X, Sodroski J. Biochemical and biophysical characterization of a chimeric TRIM21-TRIM5alpha protein. J Virol. 2008 Dec;82(23):11669-81. doi: 10.1128/JVI.01559-08. Epub 2008 Sep 17. PubMed PMID: 18799572; PubMed Central PMCID: PMC2583655.
19. Taube R, Zhu Q, Xu C, Diaz-Griffero F, Sui J, Kamau E, Dwyer M, Aird D, Marasco WA. Lentivirus display: stable expression of human antibodies on the surface of human cells and virus particles. PLoS One. 2008 Sep 11;3(9):e3181. doi: 10.1371/journal.pone.0003181. PubMed PMID: 18784843; PubMed Central PMCID: PMC2527531.
18. Diaz-Griffero F, Perron M, McGee-Estrada K, Hanna R, Maillard PV, Trono D, Sodroski J. A human TRIM5alpha B30.2/SPRY domain mutant gains the ability to restrict and prematurely uncoat B-tropic murine leukemia virus. Virology. 2008 Sep 1;378(2):233-42. doi: 10.1016/j.virol.2008.05.008. Epub 2008 Jun 30. PubMed PMID: 18586294; PubMed Central PMCID: PMC2597210.
17. Diaz-Griffero F, Taube R, Muehlbauer SM, Brojatsch J. Efficient production of HIV-1 viral-like particles in mouse cells. Biochem Biophys Res Commun. 2008 Apr 11;368(3):463-9. doi: 10.1016/j.bbrc.2007.12.195. Epub 2008 Jan 30. PubMed PMID: 18241668.
16. Diaz-Griffero F, Kar A, Lee M, Stremlau M, Poeschla E, Sodroski J. Comparative requirements for the restriction of retrovirus infection by TRIM5alpha and TRIMCyp. Virology. 2007 Dec 20;369(2):400-10. Epub 2007 Oct 24. PubMed PMID: 17920096; PubMed Central PMCID: PMC2153441.
15. Javanbakht H, Diaz-Griffero F, Yuan W, Yeung DF, Li X, Song B, Sodroski J. The ability of multimerized cyclophilin A to restrict retrovirus infection. Virology. 2007 Oct 10;367(1):19-29. Epub 2007 Jun 15. PubMed PMID: 17574642; PubMed Central PMCID: PMC2065756.
14. Diaz-Griffero F, Kar A, Perron M, Xiang SH, Javanbakht H, Li X, Sodroski J. Modulation of retroviral restriction and proteasome inhibitor-resistant turnover by changes in the TRIM5alpha B-box 2 domain. J Virol. 2007 Oct;81(19):10362-78. Epub 2007 Jul 11. PubMed PMID: 17626085; PubMed Central PMCID: PMC2045480.
13. Li X, Gold B, O'hUigin C, Diaz-Griffero F, Song B, Si Z, Li Y, Yuan W, Stremlau M, Mische C, Javanbakht H, Scally M, Winkler C, Dean M, Sodroski J. Unique features of TRIM5alpha among closely related human TRIM family members. Virology. 2007 Apr 10;360(2):419-33. Epub 2006 Dec 6. PubMed PMID: 17156811.
12. Javanbakht H, Yuan W, Yeung DF, Song B, Diaz-Griffero F, Li Y, Li X, Stremlau M, Sodroski J. Characterization of TRIM5alpha trimerization and its contribution to human immunodeficiency virus capsid binding. Virology. 2006 Sep 15;353(1):234-46. Epub 2006 Jun 30. PubMed PMID: 16808955.
11. Diaz-Griffero F, Vandegraaff N, Li Y, McGee-Estrada K, Stremlau M, Welikala S, Si Z, Engelman A, Sodroski J. Requirements for capsid-binding and an effector function in TRIMCyp-mediated restriction of HIV-1. Virology. 2006 Aug 1;351(2):404-19. Epub 2006 May 2. PubMed PMID: 16650449.
10. Diaz-Griffero F, Li X, Javanbakht H, Song B, Welikala S, Stremlau M, Sodroski J. Rapid turnover and polyubiquitylation of the retroviral restriction factor TRIM5. Virology. 2006 Jun 5;349(2):300-15. Epub 2006 Feb 10. PubMed PMID: 16472833.
9. Stremlau M, Perron M, Lee M, Li Y, Song B, Javanbakht H, Diaz-Griffero F, Anderson DJ, Sundquist WI, Sodroski J. Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor. Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5514-9. Epub 2006 Mar 15. PubMed PMID: 16540544; PubMed Central PMCID: PMC1459386.
8. Díaz-Griffero F, Espinoza Cancino C, Medina Arévalo C, Arce-Johnson P. Expression of the crucifer-infecting TMV-Cg movement protein in tobacco plants complements in trans a TMV-U1 trafficking-deficient mutant. Biol Res. 2006;39(2):269-79. Epub 2006 Jul 25. PubMed PMID: 16874402.
7. Song B, Diaz-Griffero F, Park DH, Rogers T, Stremlau M, Sodroski J. TRIM5alpha association with cytoplasmic bodies is not required for antiretroviral activity. Virology. 2005 Dec 20;343(2):201-11. Epub 2005 Sep 22. PubMed PMID: 16183097.
6. Mische CC, Javanbakht H, Song B, Diaz-Griffero F, Stremlau M, Strack B, Si Z, Sodroski J. Retroviral restriction factor TRIM5alpha is a trimer. J Virol. 2005 Nov;79(22):14446-50. PubMed PMID: 16254380; PubMed Central PMCID: PMC1280198.
5. Javanbakht H, Diaz-Griffero F, Stremlau M, Si Z, Sodroski J. The contribution of RING and B-box 2 domains to retroviral restriction mediated by monkey TRIM5alpha. J Biol Chem. 2005 Jul 22;280(29):26933-40. Epub 2005 May 15. PubMedPMID: 15897199.
4. Diaz-Griffero F, Jackson AP, Brojatsch J. Cellular uptake of avian leucosis virus subgroup B is mediated by clathrin. Virology. 2005 Jun 20;337(1):45-54. PubMed PMID: 15914219.
3. Diaz-Griffero F, Hoschander SA, Brojatsch J. Bystander killing during avian leukosis virus subgroup B infection requires TVB(S3) signaling. J Virol. 2003 Dec;77(23):12552-61. PubMed PMID: 14610178; PubMed Central PMCID: PMC262550.
2. Diaz-Griffero F, Hoschander SA, Brojatsch J. Endocytosis is a critical step in entry of subgroup B avian leukosis viruses. J Virol. 2002 Dec;76(24):12866-76. PubMed PMID: 12438612; PubMed Central PMCID: PMC136682.
1. Chi Y, Diaz-Griffero F, Wang C, Young JA, Brojatsch J. An NF-kappa B-dependent survival pathway protects against cell death induced by TVB receptors for avian leukosis viruses. J Virol. 2002 Jun;76(11):5581-7. PubMed PMID: 11991986; PubMed Central PMCID: PMC137008.